Engineering RNA-based tools to probe and manipulate biological systems
Aaron Engelhart will participate in the Petri Dish event panel. https://www.eventbrite.com/e/a-new-era-for-vaccines-a-petri-dish-conversation-registration-136961642961 Wed, February 17, 2021 4:00 PM – 5:30 PM CST Join for a lively conversation about new approaches to fighting disease. It seems like the pandemic made everyone a medical expert as we latched […]
Tanner G Hoog, Lauren M Aufdembrink, Nathaniel J Gaut, Rou‐Jia Sung, Katarzyna P Adamala, Aaron E Engelhart Biochemistry and Molecular Biology Education, Volume 48, Issue 5 Special Issue: Teaching in the Time of COVID‐19. September/October 2020 Pages 448-451 Structural biology education commonly employs molecular visualization software, […]
Pavana Khan, Lauren M Aufdembrink, Aaron E Engelhart ACS Synth. Biol. 2020, 9, 11, 2861–2880 The COVID-19 pandemic, caused by the SARS-CoV-2 virus, poses grave threats to both the global economy and health. The predominant diagnostic screens in use for SARS-CoV-2 detection are molecular techniques […]
Lauren M Aufdembrink, Pavana Khan, Nathaniel J Gaut, Katarzyna P Adamala, Aaron E Engelhart RNA 2020. 26: 1283-1290 Isothermal, cell-free, synthetic biology-based approaches to pathogen detection leverage the power of tools available in biological systems, such as highly active polymerases compatible with lyophilization, without the […]
T Hoog, N Gaut, MR Pawlak, BF Bachan, AE Engelhart Mars Extant Life: What’s Next? Held 5-8 November, 2019 in Carlsbad, New Mexico. LPI Contribution No. 2108, 2019, id.5098 Here we report our investigations of the behavior of nucleic acids in the presence of high […]
Lauren M Aufdembrink, Tanner G Hoog, Matthew R Pawlak, Benjamin F Bachan, Joseph M Heili, Aaron E Engelhart Methods in Enzymology Volume 623, 2019, Pages 23-43 Thermal denaturation is a common technique in the biophysical study of nucleic acids. These experiments are typically performed by […]
Lin Jin, Aaron E Engelhart, Weicheng Zhang, Katarzyna Adamala, Jack W Szostak J. Am. Chem. Soc. 2018, 140, 44, 15016–15021 The study of nonenzymatic template-directed RNA copying is the experimental basis for the search for chemistry and reaction conditions consistent with prebiotic RNA replication. The […]
Joseph M Heili, Jose Gomez-Garcia, Nathaniel J Gaut, Brock W Cash, Lauren M Aufdembrink, Brent A Heffron, Joshua D Shirley, Erin E Carlson, Katarzyna P Adamala, Aaron E Engelhart Journal of Chemical Education, 2018, 95, 10, 1867–1871 A teaching laboratory experiment is described where students […]
Congratulations Nate!
Preparation, Purification, and Use of Fatty Acid-containing Liposomes (News and Views) Aaron E. Engelhart Journal of Visualized Experiments, 2018. doi:10.3791/57324 Publisher | ResearchGate | PubMed | Google Scholar | Free Readcube Link to Paper Liposomes containing single-chain amphiphiles, particularly fatty acids, exhibit distinct properties compared […]