Collaboration between primitive cell membranes and soluble catalysts Katarzyna P. Adamala, Aaron E. Engelhart (joint first author), and Jack W. Szosta...
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A simple physical mechanism enables homeostasis in primitive cells Aaron E. Engelhart, Katarzyna P. Adamala, and Jack W. Szostak Nature Chemistry, 201...
Read MoreA simple physical mechanism enables homeostasis in primitive cells (Nature Chemistry 2016)
Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations Katarzyna Adamala, Aaron E Engelhart (Shared...
Read MoreConstruction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations (Nature Protocols 2015)
Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension Katarzyna Adamala, Aaron E. Engelhart, and Jac...
Read MoreGeneration of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension (JACS 2015)
Structural insights into the effects of 2′-5′ linkages on the RNA duplex Jia Sheng, Li Li, Aaron E. Engelhart, Jianhua Gan, Jiawei Wang, and Jack ...
Read MoreStructural insights into the effects of 2′-5′ linkages on the RNA duplex (PNAS 2014)
Ester Formation and Hydrolysis during Wet–Dry Cycles: Generation of Far-from-Equilibrium Polymers in a Model Prebiotic Reaction Irena Mamajanov, Pat...
Read MoreEster formation and hydrolysis during wet–dry cycles: Generation of far-from-equilibrium polymers in a model prebiotic reaction (Macromolecules 2014)
Functional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity Aaron E. Engelhart, Matthew W. Powner & ...
Read MoreFunctional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity (Nature Chemistry 2013)
Nonenzymatic Ligation of DNA with a Reversible Step and a Final Linkage that Can Be Used in PCR Aaron E. Engelhart, Brian J. Cafferty, C. Denise Okafo...
Read MoreNonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR (ChemBioChem 2012)
DNA and RNA in Anhydrous Media: Duplex, Triplex, and G-Quadruplex Secondary Structures in a Deep Eutectic Solvent (featured on Frontispiece) Irena Mam...
Read MoreDNA and RNA in anhydrous media: duplex, triplex, and G-Quadruplex secondary structures in a deep eutectic solvent (Angewandte Chemie 2010)
Primitive Genetic Polymers Aaron E. Engelhart and Nicholas V. Hud Cold Spring Harbor Perspectives in Biology, 2010. doi: 10.1101/cshperspect.a002196 P...
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