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My publications are listed below. The title of each links to a page with more detailed information. I have written 
abstracts targeted to the lay public for each publication, which can be found at each publication’s webpage. Please feel free to contact me with any questions about my work.
Full product list: google scholar.
DNA G-quadruplexes are uniquely stable in the presence of denaturants and monovalent cations
TG Hoog, MR Pawlak, BF Bachan, AE Engelhart
2022; Biochemistry and biophysics reports 30, 101238
Switchable DNA‐Based Peroxidases Controlled by a Chaotropic Ion
TG Hoog, MR Pawlak, LM Aufdembrink, BR Bachan, MB Galles, …
2022; ChemBioChem, e202200090
Akaby—Cell-free protein expression system for linear templates
W Sato, J Sharon, C Deich, N Gaut, B Cash, AE Engelhart, KP Adamala
2022; PloS one 17 (4), e0266272
Programmable Fusion and Differentiation of Synthetic Minimal Cells
NJ Gaut, J Gomez-Garcia, JM Heili, B Cash, Q Han, AE Engelhart, …
2022; ACS Synthetic Biology 11 (2), 855-866
Expanding luciferase reporter systems for cell-free protein expression
W Sato, M Rasmussen, C Deich, AE Engelhart, KP Adamala
2022; bioRxiv
Parasites, infections and inoculation in synthetic minimal cells
B Cash, NJ Gaut, C Deich, LL Johnson, AE Engelhart, KP Adamala
2022; bioRxiv
Controlled exchange of protein and nucleic acid signals from and between synthetic minimal cells
JM Heili, K Stokes, NJ Gaut, C Deich, J Gomez-Garcia, B Cash, …
2022; bioRxiv
Salty Environments: The importance of evaporites and brine environments as habitats and preservers of biosignatures
S Perl, S Adeli, C Basu, BK Baxter, J Bowman, E Boyd, M Cable, …
2021; Bulletin of the American Astronomical Society 53 (4), 240
T7Max transcription system
C Deich, B Cash, W Sato, J Sharon, L Aufdembrink, NJ Gaut, J Heili, …
2021; bioRxiv
Minimal DNA Electron Transfer Catalysts Switched by a Chaotropic Ion
TG Hoog, MR Pawlak, LM Aufdembrink, BR Bachan, MB Galles, …
2021; bioRxiv, 784561
Isothermal SARS-CoV-2 diagnostics: tools for enabling distributed pandemic testing as a means of supporting safe reopenings
P Khan, LM Aufdembrink, AE Engelhart
2020; ACS Synthetic Biology 9 (11), 2861-2880
Rapid deployment of smartphone‐based augmented reality tools for field and online education in structural biology
TG Hoog, LM Aufdembrink, NJ Gaut, RJ Sung, KP Adamala, AE Engelhart
2020; Biochemistry and Molecular Biology Education 48 (5), 448-451
Highly specific, multiplexed isothermal pathogen detection with fluorescent aptamer readout
LM Aufdembrink, P Khan, NJ Gaut, KP Adamala, AE Engelhart
2020; Rna 26 (9), 1283-1290
Mars extant life: what’s next? Conference Report
BL Carrier, DW Beaty, MA Meyer, JG Blank, L Chou, S DasSarma, …
2020; Astrobiology 20 (6), 785-814
Mars as a Prebiotic Chemistry Laboratory: A Martian RNA World?
T Hoog, N Gaut, MR Pawlak, BF Bachan, AE Engelhart
2019; Mars Extant Life: What’s Next? 2108, 5098
DNA transistors switched by the Hofmeister effect
TG Hoog, MR Pawlak, LM Aufdembrink, BR Bachan, MB Galles, …
2019; bioRxiv, 784561
The RNA World on Mars
A Engelhart, N Gaut, M Pawlak, B Bachan, K Adamala
2019; 2019 Astrobiology Science Conference
Differentiation of pluripotent synthetic minimal cells via genetic circuits and programmable mating
NJ Gaut, J Gomez-Garcia, JM Heili, B Cash, Q Han, AE Engelhart, …
2019; bioRxiv, 712968
Methods for thermal denaturation studies of nucleic acids in complex with fluorogenic dyes
LM Aufdembrink, TG Hoog, MR Pawlak, BF Bachan, JM Heili, …
2019; Methods in Enzymology 623, 23-43
Catalysis of template-directed nonenzymatic RNA copying by Iron (II)
L Jin, AE Engelhart, W Zhang, K Adamala, JW Szostak
2018; Journal of the American Chemical Society 140 (44), 15016-15021
Real-Time Visualization of in Vitro Transcription of a Fluorescent RNA Aptamer: An Experiment for the Upper-Division Undergraduate or First-Year Graduate …
JM Heili, J Gomez-Garcia, NJ Gaut, BW Cash, LM Aufdembrink, …
2018; Journal of Chemical Education 95 (10), 1867-1871
Preparation, purification, and use of fatty acid-containing liposomes
L Jin, AE Engelhart, KP Adamala, JW Szostak
2018; JoVE (Journal of Visualized Experiments), e57324
A tale of two G-quadruplexes
AE Engelhart
2017; Nature Chemical Biology 13 (11), 1140-1141
Pre-LUCA cells: life but not alive
N Gaut, J Heili, J Gomez-Garcia, A Engelhart, K Adamala
2017; XVIIIth International Conference on the Origin of Life 1967, 4200
Functional Interactions Between Early Biopolymers and Primitive Cells
J Heili, N Gaut, Q Han, J Gomez-Garcia, JW Szostak, KP Adamala, …
2017; XVIIIth International Conference on the Origin of Life 1967, 4207
A simple physical mechanism enables homeostasis in primitive cells
AE Engelhart, KP Adamala, JW Szostak
2016; Nature chemistry 8 (5), 448-453
Collaboration between primitive cell membranes and soluble catalysts
KP Adamala, AE Engelhart, JW Szostak
2016; Nature communications 7 (1), 1-7
Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations
K Adamala, AE Engelhart, NP Kamat, L Jin, JW Szostak
2015; Nature protocols 10 (6), 927-938
Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension
K Adamala, AE Engelhart, JW Szostak
2015; Journal of the American Chemical Society 137 (1), 483-489
Structural insights into the effects of 2′-5′ linkages on the RNA duplex
J Sheng, L Li, AE Engelhart, J Gan, J Wang, JW Szostak
2014; Proceedings of the National Academy of Sciences 111 (8), 3050-3055
Ester formation and hydrolysis during wet–dry cycles: generation of far-from-equilibrium polymers in a model prebiotic reaction
I Mamajanov, PJ MacDonald, J Ying, DM Duncanson, GR Dowdy, …
2014; Macromolecules 47 (4), 1334-1343
Functional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity
AE Engelhart, MW Powner, JW Szostak
2013; Nature chemistry 5 (5), 390-394
Crystal structure studies of RNA molecules containing 2′–5′-linkages
J Sheng, L Li, AE Engelhart, JW Szostak
2013; Journal of Biomolecular Structure and Dynamics 31 (sup1), 4-4
Imperfect RNA synthesis via model prebiotic reactions and consequences for functional RNAs
AE Engelhart, MW Powner, JW Szostak
2013; Journal of Biomolecular Structure and Dynamics 31 (sup1), 4-5
Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR
AE Engelhart, BJ Cafferty, CD Okafor, MC Chen, LD Williams, DG Lynn, …
2012; ChemBioChem 13 (8), 1121-1124
PCR amplification of a DNA construct formed by a ligation system which employs a reversible linkage
BJ Cafferty, AE EngelHart, D Okafor, DG Lynn, NV Hud
2012; ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243
Nucleic acid assembly, polymerization, and ligand binding
AE Engelhart
2012; Georgia Institute of Technology
Primitive genetic polymers
AE Engelhart, NV Hud
2010; Cold Spring Harbor Perspectives in Biology 2 (12), a002196
DNA and RNA in anhydrous media: Duplex, triplex, and G‐quadruplex secondary structures in a deep eutectic solvent
I Mamajanov, AE Engelhart, HD Bean, NV Hud
2010; Angewandte Chemie International Edition 49 (36), 6310-6314
Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world
ED Horowitz, AE Engelhart, MC Chen, KA Quarles, MW Smith, DG Lynn, …
2010; Proceedings of the National Academy of Sciences 107 (12), 5288-5293
Reversible Backbone Linkages and Intercalators as Key Components of the Proto-RNA World
AE Engelhart, ED Horowitz, D Lynn, NV Hud
2009; JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 26 (6), 815-815
Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites
AG Tsai, AE Engelhart, MH Ma’mon, SI Houston, NV Hud, IS Haworth, …
2009; Journal of Biological Chemistry 284 (11), 7157-7164
Sequence-specific DNA-metal ion interactions
NV Hud, AE Engelhart
2009; Nucleic acid-metal ion interactions, 75-117
Evidence of strong hydrogen bonding by 8-aminoguanine
AE Engelhart, TH Morton, NV Hud
2009; Chemical communications, 647-649
Nanomolar Selective G Quadruplex Ligands from One Pot Thermodynamic and Structural Studies of Azacyanines
A Engelhart, Ö Persil Çetinkol, R Nanjunda, D Wılson, N Hud
2008;
Metal ion interactions with G-quadruplex structures
AE Engelhart, J Plavec, O Persil, NV Hud
2008; Nucleic acid–metal ion interactions, 118-153
Submicromolar, Selective G‐Quadruplex Ligands from One Pot: Thermodynamic and Structural Studies of Human Telomeric DNA Binding by Azacyanines
Ö Persil Çetinkol, AE Engelhart, RK Nanjunda, WD Wilson, NV Hud
2008; ChemBioChem 9 (12), 1889-1892