DNA and RNA in anhydrous media: duplex, triplex, and G-Quadruplex secondary structures in a deep eutectic solvent (Angewandte Chemie 2010)

DNA and RNA in Anhydrous Media: Duplex, Triplex, and G-Quadruplex Secondary Structures in a Deep Eutectic Solvent (featured on Frontispiece) Irena Mamajanov, Aaron E. Engelhart, Heather D. Bean and Nicholas V. Hud Angewandte Chemie International Edition in English, 2010, 49 (36), pp 6310-6314. doi: 10.1002/anie.201001561 […]

Primitive genetic polymers (Cold Spring Harbor Perspectives in Biology 2010)

Primitive Genetic Polymers Aaron E. Engelhart and Nicholas V. Hud Cold Spring Harbor Perspectives in Biology, 2010. doi: 10.1101/cshperspect.a002196 Publisher | ResearchGate | PubMed | Google Scholar Scientific Abstract Since the structure of DNA was elucidated more than 50 years ago, Watson-Crick base pairing has […]

Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world (PNAS 2010)

Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world Eric D. Horowitz, Aaron E. Engelhart (Shared first author), Michael C. Chen, Kaycee A. Quarles, Michael W. Smith, David G. Lynn, and Nicholas V. Hud Proceedings of the […]

Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites (J. Biol. Chem. 2009)

Conformational Variants of Duplex DNA Correlated with Cytosine-rich Chromosomal Fragile Sites Albert G. Tsai, Aaron E. Engelhart, Ma’mon M. Hatmal, Sabrina I. Houston, Nicholas V. Hud, Ian S. Haworth, and Michael R. Lieber Journal of Biological Chemistry, 2009, 284, pp 7157-7164. doi: 10.1074/jbc.M806866200 Publisher | […]

Evidence of strong hydrogen bonding by 8-aminoguanine (ChemComm 2009)

Evidence of strong hydrogen bonding by 8-aminoguanine (front cover article) Aaron E. Engelhart, Thomas Hellman Morton, and Nicholas V. Hud ChemComm, 2009, 6, pp 647-649. doi: 10.1039/B818409G Publisher | ResearchGate | PubMed | Google Scholar Scientific Abstract Of the molecular recognition tools available to supramolecular […]

Metal ion interactions with G-Quadruplex structures (RSC Book Chapter 2009)

Metal Ion Interactions with G-Quadruplex Structures Aaron E. Engelhart, Janez Plavec, Özgül Persil and Nicholas V. Hud in Nucleic Acid-Metal Ion Interactions (RSC Publishing), 2009, 118-153. doi: 10.1039/9781847558763-00118 Publisher | ResearchGate | Google Scholar (Book) Review in Angewandte Chemie International Edition in English | Review […]

Sequence-Specific DNA-Metal Ion Interactions (RSC Book Chapter 2009)

Sequence-Specific DNA-Metal Ion Interactions Nicholas V. Hud and Aaron E. Engelhart in Nucleic Acid-Metal Ion Interactions (RSC Publishing), 2009, 75-117. doi: 10.1039/9781847558763-00075 Publisher | ResearchGate | Google Scholar (Book) Review in Angewandte Chemie International Edition in English | Review in Journal of the American Chemical […]

Submicromolar, selective G-Quadruplex ligands from one pot: thermodynamic and structural studies of human telomeric DNA binding by azacyanines (ChemBioChem 2008)

Submicromolar, Selective G-Quadruplex Ligands from One Pot: Thermodynamic and Structural Studies of Human Telomeric DNA Binding by Azacyanines Özgül Persil Çetinkol, Aaron E. Engelhart (shared first author), Rupesh K. Nanjunda, W. David Wilson, and Nicholas V. Hud ChemBioChem, 2008, 9 (12), pp 1889-1892. doi: 10.1002/cbic.200800234 Publisher […]